Cardiovascular and Renal Damage in Primary Aldosteronism: Outcomes After Treatment
نویسندگان
چکیده
منابع مشابه
Cardiovascular outcomes in patients with primary aldosteronism after treatment.
BACKGROUND Experimental and human studies demonstrate that long-term exposure to elevated aldosterone levels results in cardiac and vascular damage. METHODS We investigated long-term cardiovascular outcomes in patients with primary aldosteronism after surgical or medical treatment. Fifty-four patients with or without evidence of adrenal adenomas were prospectively followed up for a mean of 7....
متن کاملRenal damage in primary aldosteronism: results of the PAPY Study.
Primary aldosteronism (PA) has been associated with cardiovascular hypertrophy and fibrosis, in part independent of the blood pressure level, but deleterious effects on the kidneys are less clear. Likewise, it remains unknown if the kidney can be diversely involved in PA caused by aldosterone-producing adenoma (APA) and idiopathic hyperaldosteronism (IHA). Hence, in the Primary Aldosteronism Pr...
متن کاملLong-term renal outcomes in patients with primary aldosteronism.
CONTEXT Experimental animal studies indicate that exposure to increased aldosterone levels might result in renal damage, but the clinical evidence supporting this role of aldosterone is preliminary. OBJECTIVE To determine the long-term outcome of renal function in patients with primary aldosteronism after surgical or medical treatment. DESIGN, SETTING, AND PARTICIPANTS Prospective study con...
متن کاملRenal function in primary aldosteronism.
Renal Function in Primary Aldosteronism To the Editor: We read the interesting article of Rossi et al1 investigating the involvement of the kidney in a large group of patients with primary aldosteronism (PA) who were recruited in a multicentric, Italian study. In these patients, the authors observed greater urinary albumin excretion (UAE) and higher prevalence of microalbuminuria than in essent...
متن کاملIs it Possible to Extirpate Cardiovascular Events in Primary Aldosteronism After Surgical Treatment
It is well known that primary aldosteronism (PA) due to aldosterone-producing adenoma (APA) is a surgically curable secondary hypertension. Thus, the differential diagnosis between unilateral hyperaldosteronemia due to APA and bilateral hyperaldosteronemia due to idiopathic hyperaldosteronism (IHA) is crucial to decide surgical indication for treatment in PA patients. Adrenal venous sampling (A...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2010
ISSN: 0895-7061,1941-7225
DOI: 10.1038/ajh.2010.169